Download Files:
Products Details
Product Description
– CDK2/Bcl2-IN-1 (compound 1), a saponin and a CDK-2 inhibitor (IC50=117.6 nM) with promising cytotoxicity against cancer cells. CDK2/Bcl2-IN-1 also inhibits Bcl-2, and induces apoptosis in A549 lung cancer cells[1].
Web ID
– HY-149436
Shipping
– Room temperature
Molecular Formula
– C35H56O10S
References
– [1]Eltamany EE, et al. A New Saponin (Zygo-albuside D) from Zygophyllum album Roots Triggers Apoptosis in Non-Small Cell Lung Carcinoma (A549 Cells) through CDK-2 Inhibition. ACS Omega. 2023 Aug 8;8(33):30630-30639.
Molecular Weight
– 668.88
SMILES
– CC1=CC[C@@]2(C(O[C@@H]3[C@@H](OS(=O)(O)=O)[C@H](O)[C@H](O)CO3)=O)CC[C@@]4(C)[C@]5(C)CCC6C(C)(C)[C@@H](O)CC[C@]6(C)C5CCC4C2[C@H]1C
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– CDK
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
