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Products Details
Product Description
– CDK2/4/6-IN-2 is a CKD2/4/6 inhibitor, with IC50 values less than 1 μM, 10 nM, 100 nM respectively[1].
Web ID
– HY-148214
Shipping
– Room temperature
Molecular Formula
– C25H30FN9
References
– [1]Hu Zhilong, et al. Preparation of pyrimidine derivatives and related heterocycles as CDK inhibitors for the treatment of cancer. Patent. WO2020224568 A1
CAS Number
– 2531748-80-6
Molecular Weight
– 475.56
SMILES
– CC(N1CCN(C2=CN=C(NC3=NC=CC(C4=CC5=C(N=CN5C(C)C)C(F)=N4)=N3)C=C2)CC1)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– CDK
Isoform
– CDK2;CDK4;CDK6
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
