Download Files:
Products Details
Product Description
– CDK2/4/6-IN-1(example 29) is a CDK2/4/6 inhibitor with IC50 values of 2.5, 23.7 and 44.3 nM for CDK2, CDK4 and CDK6, respectively. CDK2/4/6-IN-1 can be used in cancer research[1]. CDK2/4/6-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Web ID
– HY-148213
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C22H22N4O4S
References
– [1]ZHANG YAN, et al. Cdk2/4/6 inhibitor, preparation method therefor, and application thereof. WO2022152259 A1.
CAS Number
– 2803837-13-8
Molecular Weight
– 438.50
SMILES
– O=S(C1=CC=C(NC2=NC=C3C(N([C@@H]4CCC[C@]4(O)C)C(C(C#C)=C3)=O)=N2)C=C1)(C)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– CDK
Isoform
– CDK2;CDK4;CDK6
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
