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Products Details
Product Description
– Cdc7-IN-18 (compound 1-2) is a potent CDC7 inhibitor with an IC50 of 1.29 nM for Cdc7/DBF4 enzyme. Cdc7-IN-18 shows antiproliferative activities with IC50 of 53.62 nM in COLO205 cells[1].
Web ID
– HY-143432
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C19H21N5OS
References
– [1]Li Gang, et al. Tetracyclic compounds as cdc7 inhibitors. WO2020239107A1.
CAS Number
– 2562329-14-8
Molecular Weight
– 367.47
SMILES
– O=C1C2=C(NC([C@]3([H])N4CCC(CC4)C3)=N1)C5=C(C6=CNN=C6CCC5)S2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– CDK
Isoform
– CDC
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
