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Products Details
Product Description
– Cdc7-IN-12 (compound 1) is a potent CDC7 inhibitor with an IC50 of <1 nM. Cdc7-IN-12 shows antiproliferative activities with IC50 of 100-1000 nM in COLO205 cells. Cdc7-IN-12 has the potential for the research of cancer[1].
Web ID
– HY-143385
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C16H14N2O2S
References
– [1]Huang XIanhai, et al. Heterocyclic pericondensed cdc7 kinase inhibitors for the treatment of cancer. WO2022055963A1.
CAS Number
– 2764865-33-8
Molecular Weight
– 298.36
SMILES
– CC1=C2CCCOC3=C(SC(C(N1)=O)=C23)C4=CC=NC=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– CDK
Isoform
– CDC
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
