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CD73-IN-4

$400$3,400

Products Details

Product Description

– CD73-IN-4 is a potent and selective methylenephosphonic acid CD73 inhibitor, with an IC50 of 2.6 nM for human CD73. CD73-IN-4 is potential for the research of cancer immunology[1].

Web ID

– HY-131967

Storage Temperature

– -20°C, 3 years (Powder)

Shipping

– Blue Ice

Applications

– COVID-19-immunoregulation

Molecular Formula

– C16H23ClN5O7P

References

– [1]Ehesan U Sharif , et al. Discovery of Potent and Selective Methylenephosphonic Acid CD73 Inhibitors. J Med Chem. 2021 Jan 5.

CAS Number

– 2216764-29-1

Molecular Weight

– 463.81

Compound Purity

– 99.54

SMILES

– ClC1=NC(N([C@@H]([C@H](O)[C@@H]2O)O[C@@H]2COCP(O)(O)=O)N=C3)=C3C(NC4CCCC4)=N1

Clinical Information

– No Development Reported

Research Area

– Cancer; Inflammation/Immunology

Solubility

– DMSO : 125 mg/mL (ultrasonic)

Target

– CD73

Pathway

– Immunology/Inflammation

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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