Products Details

Product Description

– CCR7 antagonist 1 (30c) is a dual CXCR2 (IC50 of 11.02 μM) and CCR7 (IC50 of 0.43 μM) antagonist[1].

Web ID

– HY-149096

Shipping

– Room temperature

Molecular Formula

– C13H22N6OS

References

– [1]Max Van Hoof, et al. Optimization of triazolo[4,5-d]pyrimidines towards human CC chemokine receptor 7 (CCR7) antagonists. Eur J Med Chem. 2023 May 5;251:115240.

Molecular Weight

– 310.42

SMILES

– CCCCCCSC1=NC(N[C@H](C)CO)=C2N=NNC2=N1

Clinical Information

– No Development Reported

Research Area

– Others

Solubility

– 10 mM in DMSO

Target

– CXCR

Pathway

– GPCR/G Protein;Immunology/Inflammation

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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