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CCR5 antagonist 3
SKU
HY-152132-Get quote
Category Reference compound
Tags Anti-infection;GPCR/G Protein;Immunology/Inflammation, CCR;HIV, Infection
Products Details
Product Description
– CCR5 antagonist 3 (Compound 26) is a CCR5 antagonist with an IC50 of 15.90 nM. CCR5 antagonist 3 shows broad-spectrum anti-HIV-1 activities[1].
Web ID
– HY-152132
Shipping
– Room temperature
Molecular Formula
– C30H41F2N5O2S
References
– [1]Xie X, et al. Structure-Based Design of Tropane Derivatives as a Novel Series of CCR5 Antagonists with Broad-Spectrum Anti-HIV-1 Activities and Improved Oral Bioavailability. J Med Chem. 2022 Dec 22;65(24):16526-16540.
CAS Number
– 1800570-92-6
Molecular Weight
– 573.74
SMILES
– CC(N(C1)CCC2=C1N=C(C)N2[C@@H]3C[C@H]4N(CC[C@@H](C5=CSC=C5)NC(C6CCC(F)(CC6)F)=O)[C@@H](C3)CC4)=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– CCR;HIV
Isoform
– CCR5;HIV-1
Pathway
– Anti-infection;GPCR/G Protein;Immunology/Inflammation
Product type
– Reference compound
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