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Products Details
Product Description
– CCR1 antagonist 10 (example 1) is a potent and orally active CCR1 antagonist. CCR1 antagonist 10 inhibits 125I-MIP-1α binding to THP-1 cell membranes with an Ki value of 2.3 nM[1].
Web ID
– HY-15544
Shipping
– Room temperature
Molecular Formula
– C30H31ClN2O4
References
– [1]Kenneth G. Carson, et al. Ccr1 antagonists for the treatment of i.a. demyelinating inflammatory disease. WO2004043965A1.
CAS Number
– 1010731-97-1
Molecular Weight
– 519.03
SMILES
– O=C(C1=CC=C(OCC2=NC=CC=C2/C3=CCCN4CC(C)(C)[C@@](O)(C5=CC=C(Cl)C=C5)CC4)C3=C1)O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– CCR
Isoform
– CCR1
Pathway
– GPCR/G Protein;Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
