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Product Description
– CCR-11 is an antibacterial agent. CCR-11 can inhibit the proliferation of B. subtilis cells with an IC50 value of 1.2 μM. CCR-11 inhibits HeLa cell proliferation with an IC50 value of 18.1 μM. CCR-11 inhibits bacterial cytokinesis by inhibiting FtsZ assembly. CCR-11 can be used for the research of FtsZ-targeted antibacterial agents[1].
Web ID
– HY-119648
Shipping
– Room temperature
Molecular Formula
– C15H8F3NO2S2
References
– [1]Singh P, et al. A rhodanine derivative CCR-11 inhibits bacterial proliferation by inhibiting the assembly and GTPase activity of FtsZ. Biochemistry. 2012 Jul 10;51(27):5434-42.
CAS Number
– 301687-87-6
Molecular Weight
– 355.35
SMILES
– O=C1NC(S/C1=C/C2=CC=C(C3=CC=CC(C(F)(F)F)=C3)O2)=S
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
