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CCK-B Receptor Antagonist 2
$450 – $3,350
Products Details
Product Description
– CCK-B Receptor Antagonist 2, compound 15b, is a potent and orally active Gastrin/CCK-B antagonist with an IC50 value of 0.43 nM. CCK-B Receptor Antagonist 2 also inhibits gastrin/CCK-A activity with an IC50 of 1.82 μM[1].
Web ID
– HY-129357
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C27H28N6O3
References
– [1]Semple G, et al. (3R)-N-(1-(tert-butylcarbonylmethyl)-2,3-dihydro-2-oxo-5-(2-pyridyl)-1H-1,4-benzodiazepin-3-yl)-N’-(3-(methylamino)phenyl)urea (YF476): a potent and orally active gastrin/CCK-B antagonist.J Med Chem. 1997 Jan 31;40(3):331-41.
CAS Number
– 155412-88-7
Molecular Weight
– 484.55
Compound Purity
– 98.84
SMILES
– O=C(N[C@H]1C(N(CC(C(C)(C)C)=O)C2=CC=CC=C2C(C3=NC=CC=C3)=N1)=O)NC4=CC=CC(N)=C4
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– DMSO : 25 mg/mL (ultrasonic;warming;heat to 70°C)
Target
– Cholecystokinin Receptor
Isoform
– CCKBR
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
