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CbzNH-PEG8-amide-bis(pentayl-5OBz)

Products Details

Product Description

– CbzNH-PEG8-amide-bis(pentayl-5OBz) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Web ID

– HY-49206

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C114H118N4O33

References

– [1]Stephanie Baah, et al. Antibody-Drug Conjugates-A Tutorial Review. Molecules. 2021 May 15;26(10):2943.

Molecular Weight

– 2072.16

SMILES

– O=C(N[C@H](C(NC[C@H](OC(C1=CC=CC=C1)=O)[C@@H](OC(C2=CC=CC=C2)=O)[C@H](OC(C3=CC=CC=C3)=O)[C@H](OC(C4=CC=CC=C4)=O)COC(C5=CC=CC=C5)=O)=O)CCC(NC[C@H](OC(C6=CC=CC=C6)=O)[C@@H](OC(C7=CC=CC=C7)=O)[C@H](OC(C8=CC=CC=C8)=O)[C@H](OC(C9=CC=CC=C9)=O)COC(C%10=CC=CC=C%10)=O)=O)CCOCCOCCOCCOCCOCCOCCOCCOCCNC(OCC%11=CC=CC=C%11)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– ADC Linker

Isoform

– Cleavable Linker

Pathway

– Antibody-drug Conjugate/ADC Related

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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