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Products Details
Product Description
– CBP/p300-IN-21 (Compound 5d) is a selective CBP/p300 inhibitor (IC50: 0.07 and 1.755 μM for p300 and CBP). CBP/p300-IN-21 decreases H3K18Ac level. CBP/p300-IN-21 inhibits growth of 4T1 tumor growth in mice[1].
Web ID
– HY-155229
Shipping
– Room temperature
Molecular Formula
– C19H16ClNO4
References
– [1]Zhong X, et al. Discovery of berberine analogs as potent and highly selective p300/CBP HAT inhibitors. Bioorg Chem. 2023 Sep;138:106597.
CAS Number
– 1065581-69-2
Molecular Weight
– 357.79
SMILES
– OC(C(OC)=C1)=CC(C1=C2)=CC3=[N+]2CCC4=CC(OCO5)=C5C=C43.[Cl-]
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Epigenetic Reader Domain;Histone Acetyltransferase
Pathway
– Epigenetics
Product type
– Reference compound
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