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Products Details
Product Description
– Cbl-b-IN-12 (Example 10) is a casitas B-lineage lymphoma-b (CBL-B) inhibitor with an IC50 of <100 nM[1].
Web ID
– HY-156768
Shipping
– Room temperature
Molecular Formula
– C28H29F3N6O2
References
– [1]Yingzhi Bi, et al. Compounds, compositions and methods of treating cancer. Patent WO2022221704A1.
CAS Number
– 2851871-29-7
Molecular Weight
– 538.56
SMILES
– O=C1N(C2=CC=CC(C3(CC4=NN=CN4C)COC3)=C2)C=C5C(C(F)(F)F)=CC(CN6CCC7(CC7)C6)=CN15
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– E1/E2/E3 Enzyme
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
