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Products Details
Product Description
– Cbl-b-IN-10 (Compound 463) is a casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl inhibitor with IC50s of 6.0 nM and 3.5 nM, respectively[1].
Web ID
– HY-156766
Shipping
– Room temperature
Molecular Formula
– C31H37F3N6O
References
– [1]Jun Liang, et al. Lactams as cbl-b inhibitors. Patent WO2022169997A1.
CAS Number
– 2815225-12-6
Molecular Weight
– 566.66
SMILES
– O=C1C2=CC(CNC3(CCC3)C)=CC(C(F)(F)F)=C2CN1C4=CC(NCC)=CC(C5(CCC5)CC6=NN=CN6C)=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– E1/E2/E3 Enzyme
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
