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Products Details
Product Description
– CB2R-IN-3 is a selective antagonist of cannabinoid type 2 receptor (CB2R). CB2R-IN-3 has high affinity for human CB2R and specific selectivity for CB1R. CB2R-IN-3 can be combined with CB65 (HY-110047), the activator of CB2R. CB2R-IN-3 effectively up-regulates the expression of anti-inflammatory cytokines and down-regulates the expression of pro-inflammatory cytokines[1].
Web ID
– HY-152581
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C27H42N2O
References
– [1]Graziano G, et al. N-adamantyl-anthranil amide derivatives: New selective ligands for the cannabinoid receptor subtype 2 (CB2R). Eur J Med Chem. 2023 Feb 15;248:115109.
Molecular Weight
– 410.64
SMILES
– CCCCCNC1=C(C=C(C=C1)CCCCC)C(NC23CC4CC(C3)CC(C2)C4)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Cannabinoid Receptor
Isoform
– CB2
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
