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CB2 PET Radioligand 1
SKU
HY-155741-Get quote
Category Reference compound
Tags Cannabinoid Receptor, GPCR/G Protein;Neuronal Signaling, Neurological Disease
Products Details
Product Description
– CB2 PET Radioligand 1 (compound [18F]9) is a PET Radioligand targeting to hCB2 (Ki=7.7 nM). CB2 PET Radioligand 1 is prepared with Cu-mediated 18F-fluorination. CB2 PET Radioligand 1 shows high brain uptake in a murine model of neuroinflammation[1].
Web ID
– HY-155741
Shipping
– Room temperature
Molecular Formula
– C20H19F3N4O
References
– [1]Kallinen A, et al. Synthesis and Preclinical Evaluation of Fluorinated 5-Azaindoles as CB2 PET Radioligands. ACS Chem Neurosci. 2023 Aug 16;14(16):2902-2921.
Molecular Weight
– 388.39
SMILES
– FC1=CC(NC2=NC=C(C(N3CCC(CC3)(F)F)=O)C4=C2C=CN4C)=CC=C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Cannabinoid Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.