CAY10602

$60$396

Products Details

Product Description

– CAY10602 is a SIRT1 activator. CAY10602 dose-dependently suppresses the NF-κB-dependent induction of TNF-α by lipopolysaccharide in THP-1 cells[1].

Web ID

– HY-104073

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– COVID-19-anti-virus

Molecular Formula

– C22H15FN4O2S

References

– [1]Nayagam VM, et al. SIRT1 modulating compounds from high-throughput screening as anti-inflammatory and insulin-sensitizing agents. J Biomol Screen. 2006 Dec;11(8):959-67.

CAS Number

– 374922-43-7

Molecular Weight

– 418.44

Compound Purity

– 98.65

SMILES

– NC1=C(S(=O)(C2=CC=CC=C2)=O)C3=NC4=CC=CC=C4N=C3N1C5=CC=C(F)C=C5

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease; Inflammation/Immunology

Solubility

– DMSO : 41.67 mg/mL (ultrasonic)

Target

– Sirtuin

Isoform

– SIRT1

Pathway

– Cell Cycle/DNA Damage;Epigenetics

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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