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Products Details
Product Description
– CAXII-IN-1 (Compound 17) is a selective CA XII inhibitor with Ki values of 3.8 nM and 56.0 nM against hCA XII and hCA IX, respectively. CAXII-IN-1 shows antitumor activity[1].
Web ID
– HY-143460
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C13H7Cl2NO3S
References
– [1]Grandāne A, et al. Development of oxathiino[6,5-b]pyridine 2,2-dioxide derivatives as selective inhibitors of tumor-related carbonic anhydrases IX and XII. Eur J Med Chem. 2020 Aug 15;200:112300.
CAS Number
– 2479918-59-5
Molecular Weight
– 328.17
SMILES
– ClC1=CC(Cl)=CC(C2=CN=C(OS(C=C3)(=O)=O)C3=C2)=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Carbonic Anhydrase
Isoform
– CA XII
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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