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Products Details
Product Description
– Cav 2.2/3.2 blocker 1 (Compound 9e) is a neuronal calcium channel blocker with IC50 values of 78 μM and 80 μM against Cav2.2 and Cav3.2, respectively. Cav 2.2/3.2 blocker 1 can penetrate the CNS[1].
Web ID
– HY-147639
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C28H30N2O3
References
– [1]Cardoso FC, et al. The neuronal calcium ion channel activity of constrained analogues of MONIRO-1. Bioorg Med Chem. 2020 Sep 15;28(18):115655.
Molecular Weight
– 442.55
SMILES
– O=C(N1C2=CC=CC=C2CCC3=CC=CC=C31)C4=CC=C(OCCCN5CCOCC5)C=C4
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Calcium Channel
Isoform
– N-type calcium channel;T-type calcium channel
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
