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Products Details
Product Description
– Catharanthine Sulfate ((+)-3,4-Didehydrocoronaridine Sulfate) is an alkaloid isolated from Madagascar periwinkle, inhibits voltage-operated L-type Ca2+ channel, with anti-cancer and blood pressure-lowering activities[1].
Web ID
– HY-N0252B
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C21H26N2O6S
References
– [1]Jadhav A, et al. Catharanthine dilates small mesenteric arteries and decreases heart rate and cardiac contractility by inhibition of voltage-operated calcium channels on vascular smooth muscle cells and cardiomyocytes. J Pharmacol Exp Ther. 2013 Jun;345(3):383-92.
CAS Number
– 153230-94-5
Molecular Weight
– 434.51
SMILES
– O=C([C@@]1(C2=C3C(C=CC=C4)=C4N2)[C@](C(CC)=C5)([H])[N@](CC3)C[C@]5([H])C1)OC.O=S(O)(O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Calcium Channel
Isoform
– L-type calcium channel
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
