Casimersen

SKU HY-132584-1 mg Category Tag

$510$2,440

Products Details

Product Description

– Casimersen (SRP-4045) is an antisense oligonucleotide of the phosphorodiamidate morpholino oligomer subclass. Casimersen binds to exon 45 of dystrophin pre-mRNA, restores the open-reading frame (by skipping exon 45) resulting in the production of an internally truncated but functional dystrophin protein. Casimersen can be used for the research of Duchenne muscular dystrophy (DMD)[1].

Web ID

– HY-132584

Storage Temperature

– -20°C (Powder, stored under nitrogen, away from moisture)

Shipping

– Blue Ice

Molecular Formula

– C268H424N124O95P22

References

– [1]Shirley M. Casimersen: First Approval. Drugs. 2021;81(7):875-879. |[2]Casimersen. Am J Health Syst Pharm. 2021;78(13):1149-1150.

CAS Number

– 1422958-19-7

Molecular Weight

– 7584.00

Compound Purity

– 91.57

SMILES

– [Casimersen]

Clinical Information

– Launched

Research Area

– Others

Solubility

– H2O : 100 mg/mL (ultrasonic)

Target

– Others

Pathway

– Others

Product type

– Oligonucleotides

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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