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Products Details
Product Description
– Casimersen (SRP-4045) is an antisense oligonucleotide of the phosphorodiamidate morpholino oligomer subclass. Casimersen binds to exon 45 of dystrophin pre-mRNA, restores the open-reading frame (by skipping exon 45) resulting in the production of an internally truncated but functional dystrophin protein. Casimersen can be used for the research of Duchenne muscular dystrophy (DMD)[1].
Web ID
– HY-132584
Storage Temperature
– -20°C (Powder, stored under nitrogen, away from moisture)
Shipping
– Blue Ice
Molecular Formula
– C268H424N124O95P22
References
– [1]Shirley M. Casimersen: First Approval. Drugs. 2021;81(7):875-879. |[2]Casimersen. Am J Health Syst Pharm. 2021;78(13):1149-1150.
CAS Number
– 1422958-19-7
Molecular Weight
– 7584.00
Compound Purity
– 91.57
SMILES
– [Casimersen]
Clinical Information
– Launched
Research Area
– Others
Solubility
– H2O : 100 mg/mL (ultrasonic)
Target
– Others
Pathway
– Others
Product type
– Oligonucleotides
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.