Products Details

Product Description

– Casein kinase 1δ-IN-5 is a potent and selective protein kinase CK-1δ inhibitor with an IC50 of 47 nM. Casein kinase 1δ-IN-5 shows neuroprotective and anti-inflammatory properties both in vitro. Casein kinase 1δ-IN-5 has the potential for neurodegenerative diseases research.

Web ID

– HY-153904

Shipping

– Room temperature

Molecular Formula

– C16H11F3N2OS

References

– [1]José A Morales-Garcia, et al. Biological and Pharmacological Characterization of Benzothiazole-Based CK-1δ Inhibitors in Models of Parkinson’s Disease. ACS Omega

CAS Number

– 1579991-10-8

Molecular Weight

– 336.33

SMILES

– O=C(CC1=CC=CC=C1)NC2=NC3=C(S2)C=C(C(F)(F)F)C=C3

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Casein Kinase

Isoform

– CK1

Pathway

– Cell Cycle/DNA Damage;Stem Cell/Wnt

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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