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Products Details
Product Description
– Cariporide is a Na+/H+ Exchanger 1 (NHE-1) inhibitor. Cariporide inhibits the expression of monocyte endothelial cell adhesion and intercellular adhesion molecule-1 (ICAM-1) mediated by high glucose (HG) by inhibiting the activation of NHE-1[1].
Web ID
– HY-13412
Shipping
– Room temperature
Molecular Formula
– C13H21N3O6S2
References
– [1]Wang SX, et al. Cariporide inhibits high glucose-mediated adhesion of monocyte-endothelial cell and expression of intercellular adhesion molecule-1. Life Sci. 2006 Aug 29;79(14):1399-404.
CAS Number
– 159138-81-5
Molecular Weight
– 379.45
SMILES
– O=C(NC(N)=N)C1=CC=C(C(C)C)C(S(=O)(C)=O)=C1.CS(=O)(O)=O
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Potassium Channel;Sodium Channel
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
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