Carboxyamidotriazole

$50$590

Products Details

Product Description

– Carboxyamidotriazole (L-651582) is a cytostatic inhibitor of nonvoltage-operated calcium channels and calcium channel-mediated signaling pathways. Carboxyamidotriazole shows anti-tumor, anti-inflammatory and antiangiogenic effects[1][2].

Web ID

– HY-16126

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C17H12Cl3N5O2

References

– [1]Chen C, et al. Carboxyamidotriazole Synergizes with Bay 43-9006 to Combat Non-Small Cell Lung Cancer through Inhibition of NANOG and Aggravation of Apoptosis. J Pharmacol Exp Ther. 2017 Aug;362(2):219-229.|[2]Hussain MM, et al. J Clin Oncol. 2003 Dec 1;21(23):4356-63.

CAS Number

– 99519-84-3

Molecular Weight

– 424.66848

Compound Purity

– 99.82

SMILES

– O=C(C1=C(N)N(CC2=CC(Cl)=C(C(C3=CC=C(Cl)C=C3)=O)C(Cl)=C2)N=N1)N

Clinical Information

– Phase 3

Research Area

– Cancer; Inflammation/Immunology

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– Calcium Channel

Pathway

– Membrane Transporter/Ion Channel;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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