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Carbamazepine
$45 – $60
Products Details
Product Description
– Carbamazepine is a pressure-sensitive sodium ion channel blocker with an IC50 of 131 μM.
Web ID
– HY-B0246
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C15H12N2O
References
– [1]Willow, M. and W.A. Catterall, Inhibition of binding of [3H]batrachotoxinin A 20-alpha-benzoate to sodium channels by the anticonvulsant drugs diphenylhydantoin and carbamazepine. Mol Pharmacol, 1982. 22(3): p. 627-35.|[2]Okada, M., et al., Biphasic effects of carbamazepine on the dopaminergic system in rat striatum and hippocampus. Epilepsy Res, 1997. 28(2): p. 143-53.
CAS Number
– 298-46-4
Molecular Weight
– 236.26858
Compound Purity
– 99.93
SMILES
– O=C(N1C2=CC=CC=C2C=CC3=CC=CC=C31)N
Clinical Information
– Launched
Research Area
– Neurological Disease; Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL (ultrasonic)
Target
– Autophagy;Mitophagy;Sodium Channel
Pathway
– Autophagy;Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
