Cap-dependent endonuclease-IN-26

SKU HY-143781-Get quote Category Tags , ,

Products Details

Product Description

– Cap-dependent endonuclease-IN-26 is a cap-dependent endonuclease (CEN) inhibitor with an IC50 of 286 nM. Cap-dependent endonuclease-IN-26 shows antiviral activity against many influenza A and B strains[1].

Web ID

– HY-143781

Shipping

– Room temperature

Applications

– COVID-19-anti-virus

Molecular Formula

– C23H23N3O3

References

– [1]Masayoshi Miyagawa, et al. Synthesis and SAR Study of Carbamoyl Pyridone Bicycle Derivatives as Potent Inhibitors of Influenza Cap-dependent Endonuclease. J Med Chem. 2019 Sep 12;62(17):8101-8114.

CAS Number

– 1370238-26-8

Molecular Weight

– 389.45

SMILES

– O=C1N(C(C)C)CN(C(C2=CC=CC=C2)C3=CC=CC=C3)N4C1=C(O)C(C=C4)=O

Clinical Information

– No Development Reported

Research Area

– Infection

Solubility

– 10 mM in DMSO

Target

– Influenza Virus

Pathway

– Anti-infection

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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