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Candesartan-d5
$605
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Products Details
Product Description
– Candesartan-d5 is the deuterium labeled Candesartan. Candesartan is an angiotensin II receptor antagonist with IC50 of 0.26 nM.
Web ID
– HY-B0205S1
Shipping
– Room temperature
Molecular Formula
– C24H15D5N6O3
References
– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Pfeffer MA, et al. Effects of candesartan on mortality and morbidity in patients with chronic heart failure: the CHARM-Overall programme. Lancet. 2003 Sep 6;362(9386):759-66.|[3]Nishimura Y, et al. Chronic peripheral administration of the angiotensin II AT(1) receptor antagonist candesartan blocks brain AT(1) receptors. Brain Res. 2000 Jul 14;871(1):29-38.
CAS Number
– 1189650-58-5
Molecular Weight
– 445.48
SMILES
– [2H]C([2H])([2H])C([2H])([2H])OC1=NC2=CC=CC(C(O)=O)=C2N1CC3=CC=C(C4=C(C5=NN=NN5)C=CC=C4)C=C3
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease; Endocrinology; Cancer
Solubility
– 10 mM in DMSO
Target
– Angiotensin Receptor;Isotope-Labeled Compounds
Pathway
– GPCR/G Protein;Others
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
