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Products Details
Product Description
– CaMKP inhibitor sodium is a selective inhibitor of ROCK1 with an IC50 value of 14 nM.
Web ID
– HY-11000A
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C10H8NNaO7S2
References
– [1]Goodman KB et al Development of dihydropyridone indazole amides as selective Rho-kinase inhibitors. J Med Chem. 2007 Jan 11;50(1):6-9.|[2]Nichols RJ et al Substrate specificity and inhibitors of LRRK2, a protein kinase mutated in Parkinson’s disease. Biochem J. 2009 Oct 23;424(1):47-60.
CAS Number
– 52789-62-5
Molecular Weight
– 341.29
SMILES
– O=S(C1=C2C=CC=C(O)C2=C(N)C(S(=O)(O)=O)=C1)(O[Na])=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ROCK
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton;Stem Cell/Wnt;TGF-beta/Smad
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
