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Caldaret
$266 – $2,520
Products Details
Product Description
– Caldaret is an intracellular Ca2+ handling modulator that acts through reverse mode Na+/Ca2+ exchanger inhibition.
Web ID
– HY-100298
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C11H16N2O3S
References
– [1]Kawasumi H, et al. Caldaret, an intracellular Ca2+ handling modulator, limits infarct size of reperfused canine heart. J Pharmacol Sci. 2007 Feb;103(2):222-33.|[2]Satoh N, et al. Lusitropic effect of MCC-135 is associated with improvement of sarcoplasmic reticulum function in ventricular muscles of rats with diabetic cardiomyopathy. J Pharmacol Exp Ther. 2001 Sep;298(3):1161-6.
CAS Number
– 133804-44-1
Molecular Weight
– 256.32
Compound Purity
– 98.35
SMILES
– O=S(C1=CC(C)=CC=C1N2CCNCC2)(O)=O
Clinical Information
– Phase 2
Research Area
– Cardiovascular Disease
Solubility
– DMSO : 4.81 mg/mL (ultrasonic;warming;adjust pH to 3 with HCl;heat to 60°C)
Target
– Na+/Ca2+ Exchanger
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
