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Calcifediol (monohydrate)
$120 – $980
Products Details
Product Description
– Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), a major circulating metabolite of vitamin D3, is a potent VDR inhibitor[1][2].
Web ID
– HY-32351A
Storage Temperature
– -20°C (Powder, protect from light, stored under nitrogen)
Shipping
– Blue Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– C27H46O3
Citations
– Sci Rep. 2022 Feb 22;12(1):3014.|Front Pharmacol. 2020 Mar 31;11:200.|Int Immunopharmacol. 2023 Jun 30;122:110558.|Int J Mol Sci. 2017 Dec 19;18(12). pii: E2764.|Nat Chem Biol. 2022 Aug 18.|Proc Natl Acad Sci U S A. 2022 Apr 12;119(15):e2117004119.|Ther Adv Endocrinol. 2020 Oct 20.
References
– [1]Wei Zheng, et al. Vitamin D-induced vitamin D receptor expression induces tamoxifen sensitivity in MCF-7 stem cells via suppression of Wnt/β-catenin signaling. Biosci Rep. 2018 Dec 7;38(6):BSR20180595.|[2]Castoldi A, et al. Calcifediol-loaded liposomes for local treatment of pulmonary bacterial infections. Eur J Pharm Biopharm. 2016 Nov 22.
CAS Number
– 63283-36-3
Molecular Weight
– 418.65
Compound Purity
– 99.89
SMILES
– C=C(CC1)/C(C[C@H]1O)=CC=C2[C@@]3([H])[C@@](CCC2)(C)[C@@H]([C@H](C)CCCC(C)(C)O)CC3.O
Clinical Information
– Launched
Research Area
– Metabolic Disease
Solubility
– DMSO : 50 mg/mL (ultrasonic)
Target
– Endogenous Metabolite;VD/VDR
Isoform
– Human Endogenous Metabolite
Pathway
– Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
