Products Details

Product Description

– CAL-130 is a PI3Kδ and PI3Kγ inhibitor with IC50s of 1.3 and 6.1 nM, respectively.

Web ID

– HY-16122A

Shipping

– Room temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C23H22N8O

References

– [1]Subramaniam Prem S, et al. Targeting nonclassical oncogenes for therapy in T-ALL. Cancer cell (2012), 21(4), 459-72.

CAS Number

– 1431697-74-3

Molecular Weight

– 426.47

SMILES

– O=C1N(C2=CC=CC=C2C)C([C@H](C)NC3=C4N=CNC4=NC(N)=N3)=NC5=C1C(C)=CC=C5

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– PI3K

Isoform

– PI3Kα;PI3Kβ;PI3Kγ;PI3Kδ

Pathway

– PI3K/Akt/mTOR

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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