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Products Details
Product Description
– Cadein1, an isoquinolinium derivative, leads to a G2/M delay and caspase-dependent apoptosis in cancer cells with non- functional p53[1].
Web ID
– HY-131143
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C33H48F2INO2
References
– [1]Eun Ryoung Jang, et al. A new isoquinolinium derivative, Cadein1, preferentially induces apoptosis in p53-defective cancer cells with functional mismatch repair via a p38-dependent pathway. J Biol Chem. 2010 Jan 29;285(5):2986-95.
Molecular Weight
– 655.64
SMILES
– COC1=C(C=C2C(CCCCCCCCCCCCCCC)=[N+](CCC2=C1)CC3=C(C=CC=C3F)F)OC.[I-]
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
