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Products Details
Product Description
– C18-Ceramide can promote exocytosis of glutamate from damaged neurons. C18-Ceramide promotes cell death in glioma cells. Ceramides is involved in diverse cellular functions, such as differentiation, cell cycle progression, cell-cell adhesion, senescence, and apoptosis[1].
Web ID
– HY-100355
Shipping
– Room temperature
Molecular Formula
– C36H71NO3
References
– [1]Tang N, et al. Differential effects of ceramide species on exocytosis in rat PC12 cells. Exp Brain Res. 2007 Nov;183(2):241-7.|[2]Wang Z, et al. Overexpression of ceramide synthase 1 increases C18-ceramide and leads to lethal autophagy in human glioma. Oncotarget. 2017 Oct 23;8(61):104022-104036.
CAS Number
– 2304-81-6
Molecular Weight
– 565.95
SMILES
– CCCCCCCCCCCCCCCCCC(N[C@@H](CO)[C@H](O)/C=C/CCCCCCCCCCCCC)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Endogenous Metabolite;Others
Pathway
– Metabolic Enzyme/Protease;Others
Product type
– Reference compound
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