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Products Details
Product Description
– c-Met-IN-9, a 4-phenoxypyridine derivative, is a c-Met kinas inhibitor with an IC50 of 12 nM. c-Met-IN-9 induces cells apoptosis, and has antitumor activities[1].
Web ID
– HY-115937
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C25H19F2N5O3
References
– [1]Ju Liu, et al. Novel 4-phenoxypyridine derivatives bearing imidazole-4-carboxamide and 1,2,4-triazole-3-carboxamide moieties: Design, synthesis and biological evaluation as potent antitumor agents. Bioorg Chem. 2022 Jan 19;120:105629.
CAS Number
– 2760326-29-0
Molecular Weight
– 475.45
SMILES
– O=C(C1=CN(C2=CC=C(F)C=C2)C=N1)NC3=CC=C(OC4=CC(NC(C5CC5)=O)=NC=C4)C(F)=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;c-Met/HGFR
Pathway
– Apoptosis;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
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