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Products Details
Product Description
– c-Met-IN-2 is a potent, selective and orally available c-Met inhibitor, with an IC50 of 0.6 nM, with antitumor activity.
Web ID
– HY-101773
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C24H21FN10O
References
– [1]Zhao F, et al. Identification of 3-substituted-6-(1-(1H-[1,2,3]triazolo[4,5-b]pyrazin-1-yl)ethyl)quinoline derivatives as highly potent and selective mesenchymal-epithelial transition factor (c-Met) inhibitors via metabolite profiling-based structural optimization. Eur J Med Chem. 2017 Jul 7;134:147-158.
CAS Number
– 1635406-73-3
Molecular Weight
– 484.49
SMILES
– OCCN1N=CC(C2=CN=C3C(N(C(C4=C(F)C=C(N=CC(C5=CN(C)N=C5)=C6)C6=C4)C)N=N3)=N2)=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– c-Met/HGFR
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
