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Products Details
Product Description
– c-met-IN-1 (compound 16) is a potent and selective c-Met inhibitor, with IC50 of 1.1 nM, with antitumor activity.[1].
Web ID
– HY-101031
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C35H37FN6O5
References
– [1]Wang X, et al. Design, synthesis and biological evaluation of novel 4-(2-fluorophenoxy)quinoline derivatives as selective c-Met inhibitors. Bioorg Med Chem. 2017 Feb 1;25(3):886-896.
CAS Number
– 2084836-84-8
Molecular Weight
– 640.70
SMILES
– FC1=CC(NC(C2=CN(C3=C(OC)C=CC=C3)C=N2)=O)=CC=C1OC4=CC=NC5=CC(OCCCN6CCN(C)CC6)=C(OC)C=C54
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– c-Met/HGFR
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
