Download Files:
Products Details
Product Description
– c-Fms-IN-12 (Compound 4g) is an FMS kinase inhibitor. c-Fms-IN-12 can also inhibits c-KIT. c-Fms-IN-12 is a potential broad-spectrum anticancer agent against multiple cancer types. c-Fms-IN-12 induces A549 cell apoptosis[1].
Web ID
– HY-147864
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C30H32N6O6
References
– [1]Farag AK, et al. Diarylurea derivatives comprising 2,4-diarylpyrimidines: Discovery of novel potential anticancer agents via combined failed-ligands repurposing and molecular hybridization approaches. Bioorg Chem. 2020 Oct;103:104121.
CAS Number
– 2145102-33-4
Molecular Weight
– 572.61
SMILES
– O=C(NC1=CN=C(NC2=CC=C(N3CCOCC3)C=C2)N=C1OC4=CC=CC(OC)=C4)NC5=CC(OC)=CC(OC)=C5
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;c-Fms;c-Kit
Pathway
– Apoptosis;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
