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BX517
$80 – $550
Products Details
Product Description
– BX517 is a potent and selective inhibitor of PDK1 with IC50 of 6 nM.
Web ID
– HY-13842
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C15H14N4O2
References
– [1]Islam I, et al. Indolinone based phosphoinositide-dependent kinase-1 (PDK1) inhibitors. Part 2: optimization of BX-517. Bioorg Med Chem Lett. 2007 Jul 15;17(14):3819-25.|[2]Islam I, et al. Indolinone based phosphoinositide-dependent kinase-1 (PDK1) inhibitors. Part 1: design, synthesis and biological activity. Bioorg Med Chem Lett. 2007 Jul 15;17(14):3814-8.
CAS Number
– 850717-64-5
Molecular Weight
– 282.30
Compound Purity
– 98.0
SMILES
– NC(NC1=CC=C(NC(/C2=C(C)C3=CC=CN3)=O)C2=C1)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 27 mg/mL
Target
– PDK-1
Pathway
– PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
