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BW 245C
$140 – $300
Products Details
Product Description
– BW 245C is a prostanoid DP-receptor (DP1) agonist, used to treat stroke.
Web ID
– HY-101987
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– C19H32N2O5
References
– [1]Ahmad AS, et al. PGD<sub>2</sub> DP1 receptor stimulation following stroke ameliorates cerebral blood flow and outcomes. Neuroscience. 2014 Oct 24;279:260-8.|[2]Zhang S, et al. Prostaglandin D<sub>2</sub> receptor D-type prostanoid receptor 2 mediates eosinophil trafficking into the esophagus. Dis Esophagus. 2014 Aug;27(6):601-6.|[3]Ayabe S, et al. Prostaglandin D<sub>2</sub> inhibits collagen secretion from lung fibroblasts by activating the DP receptor. J Pharmacol Sci. 2013;121(4):312-7. Epub 2013 Mar 29.|[4]Kobayashi K, et al. Prostaglandin D<sub>2</sub>-DP signaling promotes endothelial barrier function via the cAMP/PKA/Tiam1/Rac1 pathway. Arterioscler Thromb Vasc Biol. 2013 Mar;33(3):565-71.
CAS Number
– 72814-32-5
Molecular Weight
– 368.47
Compound Purity
– 99.14
SMILES
– O=C(O)CCCCCC[C@@H](C(N1)=O)N(CC[C@H](C2CCCCC2)O)C1=O
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease; Endocrinology
Solubility
– DMSO : 50 mg/mL (ultrasonic;warming)
Target
– Prostaglandin Receptor
Isoform
– DP
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
