Download Files:
Products Details
Product Description
– BVDU 5′-Triphosphate is an antivirus agent with 5′-Triphosphate label, targeting viral DNA polymerase. BVDU 5′-Triphosphate shows excellent selectivity against varicella-zoster virus (VZV) and herpes simplex virus type 1 (HSV-1), due to a specific phosphorylation by the virus-encoded thymidine kinase.
Web ID
– HY-W747737
Shipping
– Room temperature
Molecular Formula
– C11H16BrN2O14P3
References
– [1]De Clercq E. Discovery and development of BVDU (brivudin) as a therapeutic for the treatment of herpes zoster. Biochem Pharmacol. 2004 Dec 15;68(12):2301-15.
CAS Number
– 77222-61-8
Molecular Weight
– 573.08
SMILES
– OP(OP(OP(O)(OC[C@@H]1[C@@H](O)C[C@H](N2C(NC(C(/C=C/Br)=C2)=O)=O)O1)=O)(O)=O)(O)=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– DNA/RNA Synthesis, HSV
Pathway
– Anti-infection, Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
