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Products Details
Product Description
– Bulbocapnine hydrochloride, an aporphine alkaloid, is a dopamine receptor inhibitor. Bulbocapnine hydrochloride inhibits dopamine synthesis. Bulbocapnine hydrochloride also has neuroleptic-like, anticonvulsant and antinociceptive effects[1][2][3].
Web ID
– HY-W436270
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C19H20ClNO4
References
– [1]Shin JS, et al. Inhibitory effects of bulbocapnine on dopamine biosynthesis in PC12 cells. Neurosci Lett. 1998 Mar 20;244(3):161-4.|[2]Zetler G. Neuroleptic-like, anticonvulsant and antinociceptive effects of aporphine alkaloids: bulbocapnine, corytuberine, boldine and glaucine. Arch Int Pharmacodyn Ther. 1988 Nov-Dec;296:255-81.|[3]Kohli JD,et al. Bulbocapnine is not a selective DA1 receptor antagonist. J Pharm Pharmacol. 1986 May;38(5):401-2.
CAS Number
– 632-47-3
Molecular Weight
– 361.82
SMILES
– OC1=C2C3=C(OCO4)C4=CC5=C3[C@](N(CC5)C)([H])CC2=CC=C1OC.Cl
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology, Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Dopamine Receptor
Pathway
– GPCR/G Protein, Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
