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Bufexamac
SKU
HY-B0494-100 mg
Category Reference compound
Tags Cell Cycle/DNA Damage;Epigenetics, HDAC, Inflammation/Immunology
$66 – $119
Products Details
Product Description
– Bufexamac is an inhibitor of HDAC6 and HDAC10 and has anti-inflammatory activity.
Web ID
– HY-B0494
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C12H17NO3
References
– [1]Bantscheff, M., et al., Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes. Nat Biotechnol, 2011. 29(3): p. 255-65.|[2]Kranke, B., et al., Epidemiological significance of bufexamac as a frequent and relevant contact sensitizer. Contact Dermatitis, 1997. 36(4): p. 212-5.
CAS Number
– 2438-72-4
Molecular Weight
– 223.27
Compound Purity
– 98.0
SMILES
– O=C(NO)CC1=CC=C(OCCCC)C=C1
Clinical Information
– Launched
Research Area
– Inflammation/Immunology
Solubility
– DMSO : ≥ 100 mg/mL|H2O : 0.67 mg/mL (ultrasonic)
Target
– HDAC
Isoform
– HDAC10;HDAC3;HDAC6;HDAC8
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.