Download Files:
Products Details
Product Description
– BU09059 is a potent and selective Kappa-opioid receptor antagonist with a pA2 of 8.62. BU09059 has nanomolar affinity for the κ-receptor, with 15-fold and 616-fold selectivity over μ- and δ-receptors, respectively. BU09059 significantly blocks U50488 (HY-15997B)-induced antinociception[1].
Web ID
– HY-119733
Shipping
– Room temperature
Molecular Formula
– C28H37N3O5
References
– [1]Joseph J Casal-Dominguez, et al. Characterization of BU09059: a novel potent selective κ-receptor antagonist. ACS Chem Neurosci. 2014 Mar 19;5(3):177-84.
CAS Number
– 1541206-05-6
Molecular Weight
– 495.61
SMILES
– C[C@]1(C2=CC(O)=CC=C2)[C@H](CN(CC(C(OCC)=O)NC([C@H]3CC4=CC=C(O)C=C4CN3)=O)CC1)C
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Opioid Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
