BTS

SKU HY-16690-1 g Category Tags , ,

$30$90

Products Details

Product Description

– BTS (N-Benzyl-p-toluenesulfonamide) is a potent and selective inhibitor of skeletal muscle myosin II subfragment 1 (S1) ATPase activity, with an IC50s of ~5 µM for actin- and Ca2+-stimulated myosin S1 ATPase. BTS specifically inhibits the contraction of fast skeletal muscle fibers[1][2].

Web ID

– HY-16690

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C14H15NO2S

References

– [1]Cheung A, et al. A small-molecule inhibitor of skeletal muscle myosin II. Nat Cell Biol. 2002 Jan;4(1):83-8.|[2]Shaw MA, et, al. Mechanism of inhibition of skeletal muscle actomyosin by N-benzyl-p-toluenesulfonamide. Biochemistry. 2003 May 27;42(20):6128-35.

CAS Number

– 1576-37-0

Molecular Weight

– 261.34

Compound Purity

– 99.74

SMILES

– O=S(NCC1=CC=CC=C1)(C2=CC=C(C)C=C2)=O

Clinical Information

– No Development Reported

Research Area

– Others

Solubility

– DMSO : 125 mg/mL (ultrasonic)

Target

– Myosin

Pathway

– Cytoskeleton

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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