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BTK inhibitor 8

$272

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Products Details

Product Description

– BTK inhibitor 8 (Compound 27) is a Btk inhibitor with an IC50 of 0.11 nM. BTK inhibitor 8 inhibits B cell activation in hWB with an IC50 of 2 nM[1].

Web ID

– HY-128403

Shipping

– Room temperature

Molecular Formula

– C24H23FN8O2

References

– [1]Musumeci F, et al. Pyrrolo[2,3-d]pyrimidines active as Btk inhibitors. Expert Opin Ther Pat. 2017 Dec;27(12):1305-1318.

CAS Number

– 2230724-66-8

Molecular Weight

– 474.49

SMILES

– O=C(C1=NOC(C(C)(C)C)=N1)NCC2=CC=C(C3=C4C(NC(C5=CN(C)N=C5)=C4)=NC=N3)C=C2F

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– Btk

Pathway

– Protein Tyrosine Kinase/RTK

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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