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BTK inhibitor 8
SKU
HY-128403-1mg
Category Reference compound
Tags Btk, Inflammation/Immunology, Protein Tyrosine Kinase/RTK
$272
Only 1000 item(s) left in stock.
Products Details
Product Description
– BTK inhibitor 8 (Compound 27) is a Btk inhibitor with an IC50 of 0.11 nM. BTK inhibitor 8 inhibits B cell activation in hWB with an IC50 of 2 nM[1].
Web ID
– HY-128403
Shipping
– Room temperature
Molecular Formula
– C24H23FN8O2
References
– [1]Musumeci F, et al. Pyrrolo[2,3-d]pyrimidines active as Btk inhibitors. Expert Opin Ther Pat. 2017 Dec;27(12):1305-1318.
CAS Number
– 2230724-66-8
Molecular Weight
– 474.49
SMILES
– O=C(C1=NOC(C(C)(C)C)=N1)NCC2=CC=C(C3=C4C(NC(C5=CN(C)N=C5)=C4)=NC=N3)C=C2F
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Btk
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.