Download Files:
Products Details
Product Description
– BTK inhibitor 13 (compound 8) is a potent and selective Bruton’s tyrosine kinase (BTK) inhibitor with an IC50 of 1.2 nM[1].
Web ID
– HY-130255
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C29H26FN5O3
References
– [1]Pulz R, et al. Design of Potent and Selective Covalent Inhibitors of Bruton’s Tyrosine Kinase Targeting an Inactive Conformation. ACS Med Chem Lett. 2019 Sep 6;10(10):1467-1472.
CAS Number
– 2376726-26-8
Molecular Weight
– 511.55
SMILES
– O=C(NC1=CC(F)=CC(C2=C3C(NC=C3C(CN(C)C(C=C)=O)=O)=NC=N2)=C1C)C4=CC=C(C5CC5)C=C4
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Btk
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
