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Products Details
Product Description
– BTK-IN-28 (compound PID-4) is a potent BTK inhibitor with anticancer activity. BTK-IN-28 has inhibitory effects on BTK and downstream signaling cascades and selectively inhibits Burkitt lymphoma RAMOS proliferation. BTK-IN-28 has no significant cytotoxicity towards non-tumor cells[1].
Web ID
– HY-157159
Shipping
– Room temperature
Molecular Formula
– C20H20N2O4S
References
– [1]Koraboina CP et al. Synthesis and Biological Evaluation of Oxindole Sulfonamide Derivatives as Bruton’s Tyrosine Kinase Inhibitors. ChemMedChem. 2023 Nov 2:e202300511.
Molecular Weight
– 384.45
SMILES
– O=S(C1=CC2=C(NC(/C2=C3CCOCC3)=O)C=C1)(NC4=CC=C(C)C=C4)=O
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– Btk
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
