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Products Details
Product Description
– BTK-IN-26 (compound 18) is a potent inhibitor of Bruton’s tyrosine kinase (BTK) and its C481 mutant, with IC50 values of 0.7 and 0.8 nM for BTK and BTK C481S, respectively. BTK-IN-26 can be used for cancer and autoimmune diseases research[1].
Web ID
– HY-153951S
Shipping
– Room temperature
Molecular Formula
– C27H26D3FN6O3
References
– [1]Xiangyang Chen, et al. Heterocyclic compounds as btk inhibitors. Patent, WO2022037649A1.
CAS Number
– 2762043-61-6
Molecular Weight
– 507.57
SMILES
– NC1=NC=NN2C([C@@H]3CC[C@H](CC3)CO)=NC(C4=CC=C(C=C4)CNC(C5=C(C=CC(F)=C5)OC([2H])([2H])[2H])=O)=C12
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Btk
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
