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Products Details
Product Description
– BTK-IN-10 is a potent BTK inhibitor with IC50s of <5 nM for wild-type BTK or mutated BTK (C481S), respectively (WO2022012509A1; example 111)[1].
Web ID
– HY-147580
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C25H24F2N4O2
References
– [1]Chunchao Yue, et al. Compound as brain-permeable btk or her2 inhibitor, preparation method therefor, and use thereof. WO2022012509A1.
CAS Number
– 2758596-07-3
Molecular Weight
– 450.48
SMILES
– NC1=NC=CN2C(C3CCC(OC3)CO)=NC(C4=CC=C(C=C4)C(F)(C5=CC=CC=C5)F)=C12
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Btk
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
